Publications
2019:
2018:
2017:
2016:
2015:
2014:
• Kalesnykas G, Rawal AS and Kaja S. The need for relevant functional endpoints in ophthalmic drug discovery. Austin Journal of Clinical Ophthalmology 2014, 1:2.
• McCalley AE, Kaja S, Payne A, Koulen P. Resveratrol and calcium signaling: molecular mechanisms and clinical relevance. Molecules. 2014: 19, 7327-40.
• Nielsen EØ and Kaja S. GABAA Receptor Expression in the Forebrain of Ataxic Rolling Nagoya Mice. Journal of Biology and Medicine.2014: 6, 1.
• Payne AJ, Kaja S, Naumchuk Y, Kunjukunju N, Koulen P. Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina. International Journal of Molecular Sciences. 2014, 15:1865-86.
• Kaja S, Naumchuk Y, Grillo SL, Borden PK, Koulen P. Differential up-regulation of Vesl-1/Homer 1 protein isoforms associated with decline in visual performance in a preclinical glaucoma model. Vision Research. 2014, 94C:16-23.
2013:
• Payne AJ, Gerdes BC, Kaja S, Koulen P. Bicistronic mammalian expression vectors containing optogenetic markers: Effect of insert sequence length on transfection efficiency and differential effects on gene expression levels. International Journal of Molecular and Cellular Biology. 2013, 4:201-208.
• Payne AJ, Gerdes BC, Naumchuk Y, McCalley AE, Kaja S, Koulen P. Presenilins regulate the cellular activity of ryanodine receptors differentially through isotype-specific N-terminal cysteines. Experimental Neurology. 2013, 250:143-150
• Payne AJ, Kaja S, Sabates NR, Koulen P. A Case for Neuroprotection Ophthalmology: Developments in Translational Research. Missouri Medicine. 2013, 110:429-436
• Kaja S, Sumien N, Borden PK, Khullar N, Iqbal M, Collins JL, Forster MJ, Koulen P. Homer-1a immediate early gene expression correlates with better cognitive performance in aging. AGE. 2013, 35:1799-1808
• Wacher A, Kaja S. Aggregation of microglia in 2D with String Gradient Weighted Moving Finite Elements. Mathematical Methods in The Applied Sciences. 2013, 36:1649-1663
2012:
• Romero-Suarez S, Mo C, Touchberry C, Lara N, Baker K, Craig R, Brotto L, Andresen J, Wacker M, Kaja S, Abreu E, Dillmann W, Mestril R, Brotto M, Nosek T. Hyperthermia: From Diagnostic and Treatments to New Discoveries. Recent Patents on Biotechnology 2012, 6:172-183.
• Kaja S, Hilgenberg JD, Clark JL, Shah AA, Wawwro D, Zimmermann S, Magnusson R, Koulen P. Detection of novel biomarkers for ovarian cancer with an optical nanotechnology detection system enabling label-free diagnostics. Journal of Biomedical Optics 2012, 17: 81412-21.
• Kaja S, Goad DL, Ali F, Abraham A, Rebenitsch RL, Teymoorian S, Krishna R, Koulen P. Evaluation of tensile strength of tissue adhesives and sutures for clear corneal incisions using porcine and bovine eyes, with a novel standardized testing platform. Clin Ophthalmol 2012, 6:305-9.
• Chhablani J, Kaja S, Shah VA. Smartphones in ophthalmology. Indian J Ophthalmol 2012, 60:127-31.
• Kaja S, Mafe OA, Parikh RA, Kandula P, Reddy CA, Gregg EV, Xin H, Mitchell P, Grillo MA, Koulen P. Distribution and function of polycystin-2 in mouse retinal ganglion cells. Neuroscience. 2012; 202:99-107.
• Burroughs SL, Duncan RS, Rayudu P, Kandula P, Payne AJ, Clark JL, Koulen P, Kaja S. Plate reader-based assays for measuring cell viability, neuroprotection and calcium in primary neuronal cultures. J Neurosci Methods. 2012;203:141-52011.
2011:
• Kaja S, Hilgenberg JD, Everett E, Olitsky SE, Gossage J, Koulen P. Effects of dilution and prolonged storage with preservative in a polyethylene container on Bevacizumab (Avastin™) for topical delivery as a nasal spray in anti-hereditary hemorrhagic telangiectasia and related therapies. Hum Antibodies. 2011; 20: 95-101.
• Kaja S, Hilgenberg JD, Rybalchenko V, Medina-Ortiz WE, Gregg EV, Koulen P. Polycystin-2 expression and function in adult mouse lacrimal acinar cells. Invest Ophthalmol Vis Sci. 2011;52(8):5605-11. PMCID: 3176037.
• Burroughs SL, Kaja S, Koulen P. Quantification of deficits in spatial visual function of mouse models for glaucoma. Invest Ophthalmol Vis Sci. 2011;52(6):3654-9.
• Garg P, Duncan RS, Kaja S, Zabaneh A, Chapman KD, Koulen P. Lauroylethanolamide and linoleoylethanolamide improve functional outcome in a rodent model for stroke. Neurosci Lett. 2011;492(3):134-8.
• Kaja S, Duncan RS, Longoria S, Hilgenberg JD, Payne AJ, Desai NM, Parikh RA, Burroughs SL, Gregg EV, Goad DL, Koulen P. Novel mechanism of increased Ca(2+) release following oxidative stress in neuronal cells involves type 2 inositol-1,4,5-trisphosphate receptors. Neuroscience. 2011;175:281-91.
2010:
• Kaja S, Van de Ven RC, Broos LA, Frants RR, Ferrari MD, Van den Maagdenberg AM, Plomp JJ. Severe and progressive neurotransmitter release aberrations in familial hemiplegic migraine type 1 Cacna1a S218L knock-in mice. J Neurophysiol. 2010;104(3):1445-55.
• Duncan RS, Goad DL, Grillo MA, Kaja S, Payne AJ, Koulen P. Control of intracellular calcium signaling as a neuroprotective strategy. Molecules. 2010;15(3):1168-95.
• van den Maagdenberg AM *, Pizzorusso T *, Kaja S *, Terpolilli N *, Shapovalova M, Hoebeek FE, Barrett CF, Gherardini L, van de Ven RC, Todorov B, Broos LA, Tottene A, Gao Z, Fodor M, De Zeeuw CI, Frants RR, Plesnila N, Plomp JJ, Pietrobon D, Ferrari MD. High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice. Ann Neurol. 2010; 67:85-98.
• Garg P, Duncan RS, Kaja S, Koulen P. Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke. Neuroscience. 2010;166: 252-62.
2003-2009:
• Plomp JJ, van den Maagdenberg AM, Kaja S. The ataxic Cacna1a-mutant mouse rolling nagoya: an overview of neuromorphological and electrophysiological findings. Cerebellum. 2009;8(3):222-30. PMCID: 2734259.
• Kaja S, Van De Ven RC, Frants RR, Ferrari MD, Van Den Maagdenberg AM, Plomp JJ. Reduced ACh release at neuromuscular synapses of heterozygous leaner Ca(v)2.1-mutant mice. Synapse. 2008; 62: 337-44.
• Kaja S, Hann V, Payne HL, Thompson CL. Aberrant cerebellar granule cell-specific GABAA receptor expression in the epileptic and ataxic mouse mutant, Tottering. Neuroscience. 2007;148: 115-125.
• van de Ven RC, Kaja S, Plomp JJ, Frants RR, van den Maagdenberg AM, Ferrari MD. Genetic models of migraine. Arch Neurol. 2007; 64: 643-6.
• Kaja S, van de Ven RC, van Dijk JG, Verschuuren JJ, Arahata K, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Severely impaired neuromuscular synaptic transmission causes muscle weakness in the Cacna1a-mutant mouse rolling Nagoya. Eur J Neurosci. 2007; 25: 2009-20.
• Kaja S, Todorov B, van de Ven RC, Ferrari MD, Frants RR, van den Maagdenberg AM, Plomp JJ. Redundancy of Cav2.1 channel accessory subunits in transmitter release at the mouse neuromuscular junction. Brain Res. 2007;1143:92-101.
• Kaja S, van de Ven RC, Broos LA, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Characterization of acetylcholine release and the compensatory contribution of non-Ca(v)2.1 channels at motor nerve terminals of leaner Ca(v)2.1-mutant mice. Neuroscience. 2007;144(4):1278-87.
• Todorov B, van de Ven RC, Kaja S, Broos LA, Verbeek SJ, Plomp JJ, Ferrari MD, Frants RR, van den Maagdenberg AM. Conditional inactivation of the Cacna1a gene in transgenic mice. Genesis. 2006;44(12):589-94.
• Kaja S, Van de Ven RC, Ferrari MD, Frants RR, Van den Maagdenberg AM, Plomp JJ. Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice. J Neurophysiol. 2006;95(4):2698-704.
• Kaja S, van de Ven RC, Broos LA, Veldman H, van Dijk JG, Verschuuren JJ, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Gene dosage-dependent transmitter release changes at neuromuscular synapses of CACNA1A R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness. Neuroscience. 2005;135(1):81-95.
• van den Maagdenberg AM, Pietrobon D, Pizzorusso T, Kaja S, Broos LA, Cesetti T, van de Ven RC, Tottene A, van der Kaa J, Plomp JJ, Frants RR, Ferrari MD. A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression. Neuron. 2004;41(5):701-10.
• Kaja S, Yang SH, Wei J, Fujitani K, Liu R, Brun-Zinkernagel AM, Simpkins JW, Inokuchi K, Koulen P. Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections. Invest Ophthalmol Vis Sci. 2003;44(7):3155-62.
- Rao VR, Lautz JD, Kaja S, Foecking EM, Lukács E, Stubbs EB Jr. Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2019; 60: 3613 - 3624.
- Kouzoukas DE, Schreiber JA, Tajuddin NF, Kaja S, Neafsey EJ, Kim HY, Collins MA. PARP inhibition in vivo blocks alcohol-induced brain neurodegeneration and neuroinflammatory cytosolic phospholipase A2 elevations. Neurochem Int. 2019; 129: 104497.
- Breuer EK, Fukushiro-Lopes D, Dalheim A, Burnette M, Zartman J, Kaja S, Wells C, Campo L, Curtis KJ, Romero-Moreno R, Littlepage LE, Niebur GL, Hoskins K, Nishimura MI, Gentile S. Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling. Cell Death Dis. 2019; 10:180
- Žiniauskaite A, Ragauskas S, Ghosh AK, Thapa R, Roessler AE, Koulen P, Kalesnykas G, Hakkarainen JJ, Kaja S. Manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, a superoxide dismutase mimetic, reduces disease severity in in vitro and in vivo models for dry-eye disease. Ocular Surface 2019; 17:257-261.
2018:
- Žiniauskaite A, Ragauskas S, Hakkarainen JJ, Rich CC, Baumgartner R, Kalesnykas G, Albers DS, Kaja S. Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome. Invest. Ophthalmol. Vis. Sci 2018; 59:3088-3093
- Rosen SM, Kaja S, De Alba F. Association of Transient Colorblindness With Sildenafil and Tadalafil. JAMA Ophthalmol 2018; doi: 10.1001/jamaophthalmol.2018.4716.
- Ragauskas S, Kielczewski E, Vance J, Kaja S, Kalesnykas G. In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model. JoVE 2018; 131.
2017:
- Fukushiro-Lopes DF, Hegel AD, Rao V, Wyatt D, Baker A, Breuer EK, Osipo C, Zartman JJ, Burnette M, Kaja S, Kouzoukas D, Burris S, Jones WK, Gentile S. Preclinical study of a Kv11.1 potassium channel activator as antineoplastic approach for breast cancer. Oncotarget 2017; 9: 3321-3337.
- Huang J, Romero-Suarez S, Lara N, Mo C, Kaja S, Brotto L, Dallas SL, Johnson ML, Jähn K, Bonewald LF, Brotto M. Crosstalk between MLO-Y4 osteocytes and C2C12 muscle cells is mediated by the Wnt/β-catenin pathway. JBMR Plus 2017; 1: 86-100
- Sandoval A, Duran P, Gandini MA, Andrade A, Almanza A, Kaja S, Felix R. Regulation of L-type CaV1.3 channel activity and insulin secretion by the cGMP-PKG signaling pathway. Cell Calcium 2017; 66: 1-9.
- Kaja S, Payne AJ, Naumchuk Y, Koulen P. Quantification of lactate dehydrogenase for cell viability testing using cell lines and primary cultured astrocytes. Curr Protoc Toxicol 2017; 72: 2.26.1 - 2.26.10.
- Maciulaitiene R, Pakuliene G, Kaja S, Pauza DH, Kalesnykas G, Januleviciene I. Glioprotection of Retinal Astrocytes After Intravitreal Administration of Memantine in the Mouse Optic Nerve Crush Model. Med Sci Monit 2017; 23: 1173-79 (PDF).
2016:
- Hakkarainen JJ, Reinasalo M, Ragauskas S, Seppanen A, Kaja S, Kalesnykas G. Acute cytotoxic effects of marketed ophthalmic formulations on human corneal epithelial cells. Int. J. Pharm. 2016; 511: 73-78.
- Means JC, Gerdes BC, Kaja S, Sumien N, Payne AJ, Stark DA, Borden PK, Price JL, Koulen P. Caspase-3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal Aging. Neurochem Res. 2016; 41: 2278-88.
- Richter F, Koulen P, Kaja S. N-Palmitoylethanolamine Prevents the Run-down of Amplitudes in Cortical Spreading Depression Possibly Implicating Proinflammatory Cytokine Release. Sci Rep. 2016, 6: 23481.
2015:
- Kaja S, Payne AJ, Nielsen EØ, Thompson CL, van den Maagdenberg AM, Koulen P, Snutch TP. Differential cerebellar GABAA receptor expression in mice with mutations in CaV2.1 (P/Q-type) calcium channels. Neuroscience 2015; 304: 198-208.
- Kaja S, Payne AJ, Naumchuk Y, Levy D, Zaidi DH, Altman AM, Nawazish S, Ghuman JK, Gerdes BC, Moore MA, Koulen P. Plate reader-based cell viability assays for glioprotection using primary rat optic nerve head astrocytes. Experimental Eye Research 2015; 138: 159-166.
- Rao VR, Perez-Neut M, Kaja S, Gentile S. Voltage-gated ion channels in cancer cell proliferation. Cancers 2015; 7: 849-75.
- Kaja S, Shah AA, Haji SA, Patel KB, Naumchuk Y, Zabaneh A, Gerdes BC, Kunjukunju N, Sabates NR, Cassell MA, Lord RK, Pikey KP, Poulose A, Koulen P. Nampt/PBEF/visfatin serum levels – a new biomarker for retinal blood vessel occlusions. Clinical Ophthalmology 2015, 9: 611-18.
- Kaja S, Payne AJ, Singh T, Ghuman JK, Sieck EG, Koulen P. An optimized lactate dehydrogenase release assay for screening of drug candidates in neuroscience. J Pharmacol Toxicol Methods 2015, 73: 1-6.
- Kaja S, Payne AJ, Patel KR, Naumchuk N, Koulen P. Differential subcellular Ca2+ signaling in a highly specialized subpopulation of astrocytes. Experimental Neurology 2015, 265: 59-68
- Payne AJ, Kaja S, Koulen. Regulation of ryanodine receptor-mediated calcium signaling by presenilins. Receptors and Clinical Investigation 2015, 2:e449.
- Kaja S, Sumien N, Shah VV, Puthawala I, Maynard AN, Khullar N, Payne AJ, Forster MJ, Koulen P. Loss of Spatial Memory, Learning, and Motor Function During Normal Aging Is Accompanied by Changes in Brain Presenilin 1 and 2 Expression Levels. Mol Neurobiol. 2015; 52:: 545-554.
2014:
• Kalesnykas G, Rawal AS and Kaja S. The need for relevant functional endpoints in ophthalmic drug discovery. Austin Journal of Clinical Ophthalmology 2014, 1:2.
• McCalley AE, Kaja S, Payne A, Koulen P. Resveratrol and calcium signaling: molecular mechanisms and clinical relevance. Molecules. 2014: 19, 7327-40.
• Nielsen EØ and Kaja S. GABAA Receptor Expression in the Forebrain of Ataxic Rolling Nagoya Mice. Journal of Biology and Medicine.2014: 6, 1.
• Payne AJ, Kaja S, Naumchuk Y, Kunjukunju N, Koulen P. Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina. International Journal of Molecular Sciences. 2014, 15:1865-86.
• Kaja S, Naumchuk Y, Grillo SL, Borden PK, Koulen P. Differential up-regulation of Vesl-1/Homer 1 protein isoforms associated with decline in visual performance in a preclinical glaucoma model. Vision Research. 2014, 94C:16-23.
2013:
• Payne AJ, Gerdes BC, Kaja S, Koulen P. Bicistronic mammalian expression vectors containing optogenetic markers: Effect of insert sequence length on transfection efficiency and differential effects on gene expression levels. International Journal of Molecular and Cellular Biology. 2013, 4:201-208.
• Payne AJ, Gerdes BC, Naumchuk Y, McCalley AE, Kaja S, Koulen P. Presenilins regulate the cellular activity of ryanodine receptors differentially through isotype-specific N-terminal cysteines. Experimental Neurology. 2013, 250:143-150
• Payne AJ, Kaja S, Sabates NR, Koulen P. A Case for Neuroprotection Ophthalmology: Developments in Translational Research. Missouri Medicine. 2013, 110:429-436
• Kaja S, Sumien N, Borden PK, Khullar N, Iqbal M, Collins JL, Forster MJ, Koulen P. Homer-1a immediate early gene expression correlates with better cognitive performance in aging. AGE. 2013, 35:1799-1808
• Wacher A, Kaja S. Aggregation of microglia in 2D with String Gradient Weighted Moving Finite Elements. Mathematical Methods in The Applied Sciences. 2013, 36:1649-1663
2012:
• Romero-Suarez S, Mo C, Touchberry C, Lara N, Baker K, Craig R, Brotto L, Andresen J, Wacker M, Kaja S, Abreu E, Dillmann W, Mestril R, Brotto M, Nosek T. Hyperthermia: From Diagnostic and Treatments to New Discoveries. Recent Patents on Biotechnology 2012, 6:172-183.
• Kaja S, Hilgenberg JD, Clark JL, Shah AA, Wawwro D, Zimmermann S, Magnusson R, Koulen P. Detection of novel biomarkers for ovarian cancer with an optical nanotechnology detection system enabling label-free diagnostics. Journal of Biomedical Optics 2012, 17: 81412-21.
• Kaja S, Goad DL, Ali F, Abraham A, Rebenitsch RL, Teymoorian S, Krishna R, Koulen P. Evaluation of tensile strength of tissue adhesives and sutures for clear corneal incisions using porcine and bovine eyes, with a novel standardized testing platform. Clin Ophthalmol 2012, 6:305-9.
• Chhablani J, Kaja S, Shah VA. Smartphones in ophthalmology. Indian J Ophthalmol 2012, 60:127-31.
• Kaja S, Mafe OA, Parikh RA, Kandula P, Reddy CA, Gregg EV, Xin H, Mitchell P, Grillo MA, Koulen P. Distribution and function of polycystin-2 in mouse retinal ganglion cells. Neuroscience. 2012; 202:99-107.
• Burroughs SL, Duncan RS, Rayudu P, Kandula P, Payne AJ, Clark JL, Koulen P, Kaja S. Plate reader-based assays for measuring cell viability, neuroprotection and calcium in primary neuronal cultures. J Neurosci Methods. 2012;203:141-52011.
2011:
• Kaja S, Hilgenberg JD, Everett E, Olitsky SE, Gossage J, Koulen P. Effects of dilution and prolonged storage with preservative in a polyethylene container on Bevacizumab (Avastin™) for topical delivery as a nasal spray in anti-hereditary hemorrhagic telangiectasia and related therapies. Hum Antibodies. 2011; 20: 95-101.
• Kaja S, Hilgenberg JD, Rybalchenko V, Medina-Ortiz WE, Gregg EV, Koulen P. Polycystin-2 expression and function in adult mouse lacrimal acinar cells. Invest Ophthalmol Vis Sci. 2011;52(8):5605-11. PMCID: 3176037.
• Burroughs SL, Kaja S, Koulen P. Quantification of deficits in spatial visual function of mouse models for glaucoma. Invest Ophthalmol Vis Sci. 2011;52(6):3654-9.
• Garg P, Duncan RS, Kaja S, Zabaneh A, Chapman KD, Koulen P. Lauroylethanolamide and linoleoylethanolamide improve functional outcome in a rodent model for stroke. Neurosci Lett. 2011;492(3):134-8.
• Kaja S, Duncan RS, Longoria S, Hilgenberg JD, Payne AJ, Desai NM, Parikh RA, Burroughs SL, Gregg EV, Goad DL, Koulen P. Novel mechanism of increased Ca(2+) release following oxidative stress in neuronal cells involves type 2 inositol-1,4,5-trisphosphate receptors. Neuroscience. 2011;175:281-91.
2010:
• Kaja S, Van de Ven RC, Broos LA, Frants RR, Ferrari MD, Van den Maagdenberg AM, Plomp JJ. Severe and progressive neurotransmitter release aberrations in familial hemiplegic migraine type 1 Cacna1a S218L knock-in mice. J Neurophysiol. 2010;104(3):1445-55.
• Duncan RS, Goad DL, Grillo MA, Kaja S, Payne AJ, Koulen P. Control of intracellular calcium signaling as a neuroprotective strategy. Molecules. 2010;15(3):1168-95.
• van den Maagdenberg AM *, Pizzorusso T *, Kaja S *, Terpolilli N *, Shapovalova M, Hoebeek FE, Barrett CF, Gherardini L, van de Ven RC, Todorov B, Broos LA, Tottene A, Gao Z, Fodor M, De Zeeuw CI, Frants RR, Plesnila N, Plomp JJ, Pietrobon D, Ferrari MD. High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice. Ann Neurol. 2010; 67:85-98.
• Garg P, Duncan RS, Kaja S, Koulen P. Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke. Neuroscience. 2010;166: 252-62.
2003-2009:
• Plomp JJ, van den Maagdenberg AM, Kaja S. The ataxic Cacna1a-mutant mouse rolling nagoya: an overview of neuromorphological and electrophysiological findings. Cerebellum. 2009;8(3):222-30. PMCID: 2734259.
• Kaja S, Van De Ven RC, Frants RR, Ferrari MD, Van Den Maagdenberg AM, Plomp JJ. Reduced ACh release at neuromuscular synapses of heterozygous leaner Ca(v)2.1-mutant mice. Synapse. 2008; 62: 337-44.
• Kaja S, Hann V, Payne HL, Thompson CL. Aberrant cerebellar granule cell-specific GABAA receptor expression in the epileptic and ataxic mouse mutant, Tottering. Neuroscience. 2007;148: 115-125.
• van de Ven RC, Kaja S, Plomp JJ, Frants RR, van den Maagdenberg AM, Ferrari MD. Genetic models of migraine. Arch Neurol. 2007; 64: 643-6.
• Kaja S, van de Ven RC, van Dijk JG, Verschuuren JJ, Arahata K, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Severely impaired neuromuscular synaptic transmission causes muscle weakness in the Cacna1a-mutant mouse rolling Nagoya. Eur J Neurosci. 2007; 25: 2009-20.
• Kaja S, Todorov B, van de Ven RC, Ferrari MD, Frants RR, van den Maagdenberg AM, Plomp JJ. Redundancy of Cav2.1 channel accessory subunits in transmitter release at the mouse neuromuscular junction. Brain Res. 2007;1143:92-101.
• Kaja S, van de Ven RC, Broos LA, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Characterization of acetylcholine release and the compensatory contribution of non-Ca(v)2.1 channels at motor nerve terminals of leaner Ca(v)2.1-mutant mice. Neuroscience. 2007;144(4):1278-87.
• Todorov B, van de Ven RC, Kaja S, Broos LA, Verbeek SJ, Plomp JJ, Ferrari MD, Frants RR, van den Maagdenberg AM. Conditional inactivation of the Cacna1a gene in transgenic mice. Genesis. 2006;44(12):589-94.
• Kaja S, Van de Ven RC, Ferrari MD, Frants RR, Van den Maagdenberg AM, Plomp JJ. Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice. J Neurophysiol. 2006;95(4):2698-704.
• Kaja S, van de Ven RC, Broos LA, Veldman H, van Dijk JG, Verschuuren JJ, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Gene dosage-dependent transmitter release changes at neuromuscular synapses of CACNA1A R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness. Neuroscience. 2005;135(1):81-95.
• van den Maagdenberg AM, Pietrobon D, Pizzorusso T, Kaja S, Broos LA, Cesetti T, van de Ven RC, Tottene A, van der Kaa J, Plomp JJ, Frants RR, Ferrari MD. A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression. Neuron. 2004;41(5):701-10.
• Kaja S, Yang SH, Wei J, Fujitani K, Liu R, Brun-Zinkernagel AM, Simpkins JW, Inokuchi K, Koulen P. Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections. Invest Ophthalmol Vis Sci. 2003;44(7):3155-62.